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April 11, 2008



FOR IMMEDIATE RELEASE



DEPUY SPINE INTRODUCES NEW CONCORDE™ BULLET VERTEBRAL BODY REPLACEMENT

Facilitates Easy Insertion and Resists Anterior Migration in Spinal Fusion Procedures


RAYNHAM, MA, April 11, 2008 - DePuy Spine, Inc., a Johnson & Johnson company, today announced the launch of the CONCORDE™ Bullet Vertebral Body Replacement, a new implant with a bulleted nose that facilitates easy insertion and pyramidal teeth that resist anterior migration during posterior and minimally invasive spinal fusion procedures.

The CONCORDE Bullet minimizes insertion forces, which can reduce the risk of damage to vertebral bodies. It is easy to insert between collapsed vertebral bodies and restores height. Once inserted, its pyramid-shaped teeth provide resistance to anterior migration. The patented lordotic option is designed to create 5 degrees of lordosis when placed obliquely (diagonally) across the midline.

"The CONCORDE Bullet takes the proven clinical success of the CONCORDE implant and improves on it with the bulleted nose and lordotic options," said Wade M. Ceola, M.D., of the Springfield Neurological and Spine Institute in Springfield, MO. "These are important innovations that enhance lumbar fusion procedures."

In addition, the use of carbon fiber-reinforced polymer (CFRP) in the implant allows for enlarged lateral openings, which are more than three-times larger than those in many PEEK devices.

Since the initial release of the CONCORDE Bullet last July, surgeons have implanted more than 2,000 of the devices to treat lumbar pathologies.

About DePuy Spine
DePuy Spine has worked and partnered with leading clinicians, researchers, and thought leaders to develop products to treat spine disorders for over 20 years. Today, DePuy Spine stands in the forefront of the worldwide spine market, with a substantial sales organization in the U.S. and an expanding worldwide distribution network. The company is committed to advancing the knowledge of all health care professionals and their patients in addressing spinal pathologies.

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